| University of Cape Town | Bleek and Lloyd Archives | 05/02/03 | $50,000 | Cape Town, South Africa | Public Knowledge |
| South African National Parks | Ecosystems Research and Training | 06/13/03 | $425,000 | Pretoria, South Africa | Past Programs |
| University of the Witwatersrand | Refugee Studies Centre | 06/13/03 | $360,000 | Johannesburg, South Africa | Past Programs |
| University of Cape Town | African Heritage Database | 06/11/04 | $550,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Graduate Fellowship Program | 06/17/05 | $1,000,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| University of the Witwatersrand | Postgraduate Fellowships and Mentoring | 06/16/06 | $1,250,000 | Johannesburg, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Southern Epistemologies Seminar Series | 12/14/17 | $50,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| University of the Witwatersrand | Developing Humanities Through WiSER | 05/31/18 | $500,000 | Johannesburg, South Africa | Higher Learning |
| University of Pretoria | Archives Project | 09/06/18 | $721,000 | Pretoria, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Writers/Scholars-in-Residence Programme | 09/06/18 | $679,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| University of the Western Cape | Food Politics and Culture | 12/13/18 | $890,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| University of the Western Cape | Communicating the Humanities | 06/06/19 | $500,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| University of Pretoria | Academic Staff Development | 09/13/12 | $200,000 | Pretoria, South Africa | International Higher Education and Strategic Projects |
| University of the Western Cape | Research Program in Critical Agrarian Studies | 09/13/12 | $325,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Cory Library Digitization Project | 10/03/13 | $85,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| South African National Parks | Research Bridges | 10/03/13 | $28,000 | Pretoria, South Africa | Past Programs |
| University of Cape Town | Mellon Mays Undergraduate Fellowship Program Renewal | 09/10/15 | $68,000 | Cape Town, South Africa | Higher Learning |
| University of the Western Cape | CHR - Aesthetic Education | 09/10/15 | $742,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| University of Pretoria | Transdisciplinary Fellowship Program | 09/10/15 | $336,500 | Pretoria, South Africa | International Higher Education and Strategic Projects |
| University of the Western Cape | Mellon Mays Undergraduate Fellowship | 09/15/16 | $110,000 | Bellville, South Africa | Higher Learning |
| Stellenbosch University | Indexing Transformation | 09/15/16 | $693,000 | Matieland, Stellenbosch, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | Mellon Mays Undergraduate Fellowship | 09/15/16 | $204,000 | Cape Town, South Africa | Higher Learning |
| University of the Witwatersrand | Mellon Mays Undergraduate Fellowship | 09/11/17 | $130,000 | Johannesburg, South Africa | Higher Learning |
| University of the Western Cape | Understanding SA's Constitutional Revolution | 09/11/17 | $658,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| University of Durban-Westville | Library Collection | 06/17/94 | $75,000 | Durban, South Africa | Other |
