| Council on Library and Information Resources | Digitizing Hidden Special Collections and Archives | 12/08/16 | $4,340,000 | Washington, DC, United States | Public Knowledge |
| Council on Library and Information Resources | Digitizing Hidden Special Collections and Archives | 12/10/15 | $4,340,000 | Washington, DC, United States | Public Knowledge |
| American Council of Learned Societies | Ryskamp Research Fellowships | 12/15/03 | $4,318,000 | New York, NY, United States | Higher Learning |
| Council on Library and Information Resources | Special Collections Cataloging Program II | 03/13/09 | $4,303,000 | Washington, DC, United States | Public Knowledge |
| American Council of Learned Societies | Public Postdoctoral Fellowships | 09/13/12 | $4,280,000 | New York, NY, United States | Higher Learning |
| Arizona State University | Praxes of Indigenous Knowledge & Collective Mentorship | 12/11/20 | $4,279,000 | Tempe, AZ, United States | Higher Learning |
| Council on Library and Information Resources | Special Collections Cataloging Program | 03/14/08 | $4,274,000 | Washington, DC, United States | Public Knowledge |
| Social Science Research Council | Mellon Mays Graduate Initiatives and Predoctoral Research Grants | 06/05/14 | $4,214,822 | Brooklyn, NY, United States | Higher Learning |
| Institute for Citizens and Scholars | Mellon Fellowships Program | 06/16/95 | $4,200,000 | Princeton, NJ, United States | Higher Learning |
| American Council of Learned Societies | Mellon/ACLS Community College Faculty Research Fellowships | 12/07/17 | $4,200,000 | New York, NY, United States | Higher Learning |
| University of Illinois at Urbana-Champaign | Humanities Without Walls Consortium II | 12/10/15 | $4,200,000 | Champaign, IL, United States | Higher Learning |
| Institute for Citizens and Scholars | Mellon Fellowships Program | 06/15/01 | $4,150,000 | Princeton, NJ, United States | Higher Learning |
| New England Foundation for the Arts, Inc. | National Dance Project | 03/12/21 | $4,062,000 | Boston, MA, United States | Arts and Culture |
| Social Science Research Council | International Dissertation Field Research Fellowships | 03/15/02 | $4,050,000 | Brooklyn, NY, United States | Higher Learning |
| National Philanthropic Trust | Philadelphia COVID-19 Relief | 11/17/20 | $4,010,000 | Jenkintown, PA, United States | Arts and Culture |
| George Eastman House | Advanced Residency Program - Phase III | 03/18/05 | $4,000,000 | Rochester, NY, United States | Arts and Culture |
| CultureTrust Greater Philadelphia | Monument Lab | 09/18/20 | $4,000,000 | Philadelphia, PA, United States | Other |
| Carnegie Hall Society, Inc. | Artistic Initiatives and Archives | 05/31/12 | $4,000,000 | New York, NY, United States | Arts and Culture |
| Vassar College | Anne Tatlock Endowments for Faculty Support | 03/15/12 | $4,000,000 | Poughkeepsie, NY, United States | Higher Learning |
| Council on Library and Information Resources | Digitizing Hidden Special Collections and Archives - Enabling New Scholarship Through Increasing Access to Unique Matierals | 03/12/15 | $4,000,000 | Washington, DC, United States | Public Knowledge |
| Yale University | Centers for the Study of Race and Ethnicity: Research, Teaching, and Partnerships | 12/09/19 | $4,000,000 | New Haven, CT, United States | Higher Learning |
| Council on Library and Information Resources | Cataloging Hidden Special Collections and Archives | 03/13/14 | $4,000,000 | Washington, DC, United States | Public Knowledge |
| American Philosophical Society | Research Grants in the Humanities and Social Sciences | 06/17/05 | $4,000,000 | Philadelphia, PA, United States | Higher Learning |
| ARTstor, Inc. | Collection Development Fund III | 12/17/04 | $4,000,000 | New York, NY, United States | Public Knowledge |
| Council on Library and Information Resources | Cataloging Hidden Special Collections and Archives | 03/14/13 | $4,000,000 | Washington, DC, United States | Public Knowledge |
