| University of Kentucky | Digital Restoration of the Herculaneum Papyri | 03/06/19 | $2,002,000 | Lexington, KY, United States | Public Knowledge |
| WGBH Educational Foundation | The American Archive of Public Broadcasting - Phase II | 06/06/19 | $750,000 | Boston, MA, United States | Public Knowledge |
| University of Kansas | Humanities Open Book | 03/06/19 | $129,000 | Lawrence, KS, United States | Public Knowledge |
| University of Virginia | Preservation Program | 03/14/08 | $1,500,000 | Charlottesville, VA, United States | Public Knowledge |
| Harvard University | International Inventory of Musical Sources | 03/14/08 | $157,000 | Cambridge, MA, United States | Public Knowledge |
| University of Pittsburgh | Planning Summer Institutes for Advanced Study in the Information Sciences | 01/26/09 | $100,000 | Pittsburgh, PA, United States | Public Knowledge |
| University of Virginia | Online Scholarly Editions - Shaping the Future | 03/02/09 | $20,000 | Charlottesville, VA, United States | Public Knowledge |
| University of California Press Foundation | Strengthening University Presses | 03/13/09 | $722,000 | Berkeley, CA, United States | Public Knowledge |
| University of Leeds | The Cambridge Edition of Ben Jonson Online | 03/19/10 | $246,000 | Leeds, United Kingdom | Public Knowledge |
| New York University | Moving Image Preservation | 03/19/10 | $523,000 | New York, NY, United States | Public Knowledge |
| Washington University in St. Louis | The Eyes on the Prize Preservation Project | 03/10/11 | $550,000 | St. Louis, MO, United States | Public Knowledge |
| George Mason University | Sustaining Digital Humanities Training through THATCamp | 03/15/12 | $268,000 | Fairfax, VA, United States | Public Knowledge |
| National Association for Olmsted Parks | Frederick Law Olmsted Papers | 01/22/13 | $75,000 | Washington, DC, United States | Public Knowledge |
| Georg-August-Universität Göttingen | TextGrid Implementation of SharedCanvas | 02/19/13 | $70,500 | Göttingen, Germany | Public Knowledge |
| Duke University | Duke Classics Computing Collaboratory | 03/14/13 | $500,000 | Durham, NC, United States | Public Knowledge |
| Digital Public Library of America | Sustainability Planning and Implementation | 03/13/14 | $594,000 | Boston, MA, United States | Public Knowledge |
| University of Pittsburgh | Doctoral Fellowships Supporting Research on Coherence at Scale | 03/13/14 | $726,000 | Pittsburgh, PA, United States | Public Knowledge |
| University of Oxford | Cultures of Knowledge - Phase III | 03/12/15 | $744,000 | Oxford, United Kingdom | Public Knowledge |
| The Book Arts Press, Inc. | The Andrew W. Mellon Fellowship for Diversity, Inclusion & Cultural Heritage | 06/06/19 | $1,500,000 | Charlottesville, VA, United States | Public Knowledge |
| University of Virginia | The Book Traces Project | 04/17/19 | $110,000 | Charlottesville, VA, United States | Public Knowledge |
| Boston University | Strategic Talent Development for Library Leadership | 06/19/19 | $100,000 | Boston, MA, United States | Public Knowledge |
| Brown University | Infrastructure for Digital Publishing - Phase II | 09/12/19 | $775,000 | Providence, RI, United States | Public Knowledge |
| University of Wisconsin at Madison | Campus Library and Museum Collaboration | 12/09/19 | $500,000 | Madison, WI, United States | Public Knowledge |
| University of North Texas | eBook Usage Data Trust | 12/09/19 | $1,200,000 | Denton, TX, United States | Public Knowledge |
| University of Calgary | Digital Preservation of EMIC Audio Archive II | 12/09/19 | $760,000 | Calgary, AB, Canada | Public Knowledge |
