| Massachusetts Institute of Technology | Open CourseWare | 06/15/01 | $5,500,000 | Cambridge, MA, United States | Higher Learning |
| Columbia University | Senior Humanities Professorships | 10/01/04 | $5,500,000 | New York, NY, United States | Higher Learning |
| Middlebury College | Creating Connections Consortium | 09/11/17 | $5,500,000 | Middlebury, VT, United States | Higher Learning |
| American Council of Learned Societies | Mellon Mays Undergraduate Fellowship Annual Renewals | 09/06/18 | $5,622,000 | New York, NY, United States | Higher Learning |
| Great Lakes Colleges Association, Inc. | Global Crossroads | 09/10/15 | $5,750,000 | Ann Arbor, MI, United States | Higher Learning |
| American Council of Learned Societies | MMUF Administration and Annual Institutional Renewals | 06/11/21 | $5,808,000 | New York, NY, United States | Higher Learning |
| University of Chicago | Graduate Fellowship Student Support Endowment | 12/11/07 | $6,000,000 | Chicago, IL, United States | Higher Learning |
| University of Pennsylvania | Graduate Student Support - Endowment | 09/18/08 | $6,000,000 | Philadelphia, PA, United States | Higher Learning |
| American Council of Learned Societies | Institutional Support | 03/10/11 | $6,000,000 | New York, NY, United States | Higher Learning |
| Duke University | Humanities Writ Large | 06/03/11 | $6,000,000 | Durham, NC, United States | Higher Learning |
| Wayne State University | Black Studies Faculty Enhancement Initiative | 12/08/22 | $6,000,000 | Detroit, MI, United States | Higher Learning |
| University of California at Berkeley | Graduate Fellowship Student Support Endowment | 12/11/07 | $6,000,000 | Berkeley, CA, United States | Higher Learning |
| Ithaka Harbors, Inc. | National Institute for Technology in Liberal Education - Funding | 09/17/05 | $6,000,000 | New York, NY, United States | Higher Learning |
| Institute for Citizens and Scholars | Mellon Fellowships Program I | 06/08/92 | $6,000,000 | Princeton, NJ, United States | Higher Learning |
| Columbia University | Graduate Fellowship Student Support Endowment | 12/11/07 | $6,000,000 | New York, NY, United States | Higher Learning |
| University of California at Los Angeles | Graduate Fellowship Student Support Endowment | 12/11/07 | $6,000,000 | Los Angeles, CA, United States | Higher Learning |
| Institute for Citizens and Scholars | Mellon Fellowships | 06/07/93 | $6,280,000 | Princeton, NJ, United States | Higher Learning |
| American Council of Learned Societies | Public Postdoctoral Fellows | 12/04/14 | $6,525,000 | New York, NY, United States | Higher Learning |
| Social Science Research Council | International Dissertation Research Fellowships | 09/18/08 | $6,765,000 | Brooklyn, NY, United States | Higher Learning |
| American Council of Learned Societies | Dissertation Fellowships/Fellowships for Recent Recipients of the PhD | 03/16/07 | $6,786,000 | New York, NY, United States | Higher Learning |
| American Council of Learned Societies | Public Fellows Program | 03/09/17 | $6,800,000 | New York, NY, United States | Higher Learning |
| American Council of Learned Societies | MMUF Annual Renewals | 06/06/19 | $7,290,000 | New York, NY, United States | Higher Learning |
| American Council of Learned Societies | MMUF Administration and Annual Institutional Renewals | 06/04/20 | $7,500,000 | New York, NY, United States | Higher Learning |
| American Council of Learned Societies | Mellon Centennial Fund | 12/08/16 | $8,000,000 | New York, NY, United States | Higher Learning |
| Associated Colleges of the Midwest, Inc. | Undergraduate and Faculty Fellows Program for a Diverse Professoriate | 03/12/15 | $8,100,000 | Chicago, IL, United States | Higher Learning |
