| Center for Advanced Study in the Behavioral Sciences, Inc. | Humanities Fellowships | 12/12/05 | $1,850,000 | Stanford, CA, United States | Higher Learning |
| University of California at Berkeley | University Humanities Centers | 12/12/05 | $365,000 | Berkeley, CA, United States | Higher Learning |
| Appalachian College Association | Centralized Technologies II | 12/12/05 | $180,000 | Berea, KY, United States | Higher Learning |
| Hunter College | Curriculum Review | 12/12/05 | $500,000 | New York, NY, United States | Higher Learning |
| Wesleyan University | Senior President | 12/12/05 | $200,000 | Middletown, CT, United States | Higher Learning |
| Brooklyn College | Mellon Mays Undergraduate Fellowship Program - 2006 Renewal | 12/12/05 | $120,000 | Brooklyn, NY, United States | Higher Learning |
| Columbia University | Mellon Mays Undergraduate Fellowship Program - 2006 Renewal | 12/12/05 | $90,000 | New York, NY, United States | Higher Learning |
| Hunter College | Mellon Mays Undergraduate Fellowship Program - 2006 Renewal | 12/12/05 | $100,000 | New York, NY, United States | Higher Learning |
| University of Pennsylvania | Mellon Mays Undergraduate Fellowship Program - 2006 Renewal | 12/12/05 | $323,000 | Philadelphia, PA, United States | Higher Learning |
| Wesleyan University | Mellon Mays Undergraduate Fellowship Program - 2006 Renewal | 12/12/05 | $200,000 | Middletown, CT, United States | Higher Learning |
| Morehouse College | Institution Building - Student Retention | 12/12/05 | $300,000 | Atlanta, GA, United States | Higher Learning |
| Howard University | Institution Building - Interdisciplinary Courses | 12/12/05 | $100,000 | Washington, DC, United States | Higher Learning |
| Marine Biological Laboratory | Semester in Environmental Science | 12/12/05 | $400,000 | Woods Hole, MA, United States | Higher Learning |
| Amherst College | Folger Shakespeare Library Post-Doctoral Fellowships | 12/15/06 | $400,000 | Amherst, MA, United States | Higher Learning |
| University of California at Berkeley | Development of Physical and Historical Sciences | 12/15/06 | $150,000 | Berkeley, CA, United States | Higher Learning |
| University of Michigan | Postdoctoral Fellowships | 12/15/06 | $1,973,000 | Ann Arbor, MI, United States | Higher Learning |
| University of Michigan | University Humanities Centers | 12/15/06 | $336,000 | Ann Arbor, MI, United States | Higher Learning |
| Southwestern University | National Institute for Technology in Liberal Education - Funding | 12/15/06 | $2,000,000 | Georgetown, TX, United States | Higher Learning |
| Williams College | Postdoctoral Fellowships - Endowment | 12/15/06 | $1,500,000 | Williamstown, MA, United States | Higher Learning |
| Organization for Tropical Studies, Inc. | Environmental Studies | 12/15/06 | $600,000 | Durham, NC, United States | Higher Learning |
| Morehouse College | Intensive Spanish Language Program | 12/15/06 | $330,000 | Atlanta, GA, United States | Higher Learning |
| Southwestern University | Collaborative Faculty Exchange Program | 12/15/06 | $150,000 | Georgetown, TX, United States | Higher Learning |
| American Indian College Fund | Faculty Career Enhancement Program | 12/15/06 | $450,000 | Denver, CO, United States | Higher Learning |
| Shimer College | Admissions and Enrollment Management | 10/29/07 | $50,000 | Chicago, IL, United States | Higher Learning |
| Internet Archive | Exposing and Sharing the Hidden Archive | 12/11/07 | $667,000 | San Francisco, CA, United States | Higher Learning |
