| New York Foundation for the Arts, Inc. | New York Theater Program | 03/10/11 | $3,140,000 | Brooklyn, NY, United States | Arts and Culture |
| Museum Associates | Mellon Undergraduate Curatorial Fellowship | 09/11/17 | $3,250,000 | Los Angeles, CA, United States | Arts and Culture |
| New England Foundation for the Arts, Inc. | National Dance Project | 03/12/15 | $3,300,000 | Boston, MA, United States | Arts and Culture |
| Carnegie Mellon University | Research Center on the Materials of the Artist and Conservator | 03/21/03 | $3,385,000 | Pittsburgh, PA, United States | Arts and Culture |
| Foundation of the American Institute for Conservation of Historic and Artistic Works, Inc. | Photograph Conservation - State Hermitage Museum | 03/19/10 | $3,460,000 | Washington, DC, United States | Arts and Culture |
| Merit School of Music | Chicago Musical Pathways Initiative | 09/06/18 | $3,500,000 | Chicago, IL, United States | Arts and Culture |
| Seattle Art Museum | Asian Paintings Conservation Center | 09/11/17 | $3,500,000 | Seattle, WA, United States | Arts and Culture |
| National Gallery of Art | Gallery's Building Program | 12/14/77 | $3,500,000 | Washington, DC, United States | Arts and Culture |
| Northwestern University | Northwestern University/Art Institute of Chicago Center for Scientific Studies in the Arts (NU-ACCESS) Phase 2 | 05/31/18 | $3,500,000 | Evanston, United States | Arts and Culture |
| New York City Center, Inc. | Fall for Dance Festival Endowment | 12/15/06 | $3,500,000 | New York, NY, United States | Arts and Culture |
| New England Foundation for the Arts, Inc. | National Theater Program | 03/13/14 | $3,625,000 | Boston, MA, United States | Arts and Culture |
| New York Foundation for the Arts, Inc. | New York Theater Program - Renewal | 03/14/13 | $3,750,000 | Brooklyn, NY, United States | Arts and Culture |
| New England Foundation for the Arts, Inc. | National Theater Project | 03/09/17 | $3,770,000 | Boston, MA, United States | Arts and Culture |
| Carnegie Mellon University | Art Conservation - Research Center | 12/11/07 | $3,870,000 | Pittsburgh, PA, United States | Arts and Culture |
| New England Foundation for the Arts, Inc. | National Dance Project | 12/07/17 | $3,900,000 | Boston, MA, United States | Arts and Culture |
| The Brooklyn Institute of Arts and Sciences | Costume Collection | 03/18/05 | $3,925,000 | Brooklyn, NY, United States | Arts and Culture |
| Carnegie Hall Society, Inc. | Artistic Initiatives and Archives | 05/31/12 | $4,000,000 | New York, NY, United States | Arts and Culture |
| George Eastman House | Advanced Residency Program - Phase III | 03/18/05 | $4,000,000 | Rochester, NY, United States | Arts and Culture |
| Dance Theatre of Harlem, Inc. | Artistic Initiatives and Capacity Building | 12/09/19 | $4,000,000 | New York, NY, United States | Arts and Culture |
| New England Foundation for the Arts, Inc. | National Theater Project | 12/09/19 | $4,412,000 | Boston, MA, United States | Arts and Culture |
| Alliance of Resident Theatres New York, Inc. | New York Theater Program | 03/06/19 | $4,480,000 | New York, NY, United States | Arts and Culture |
| Metropolitan Opera Association, Inc. | HD Transmissions and PBS Broadcasts | 06/13/08 | $4,750,000 | New York, NY, United States | Arts and Culture |
| United States Artists, Inc. | Artist Relief Fund | 04/09/20 | $5,000,000 | Chicago, IL, United States | Arts and Culture |
| Lincoln Center for the Performing Arts, Inc. | Endowment for New Commissions and Artistic Collaborations | 12/11/07 | $5,000,000 | New York, NY, United States | Arts and Culture |
| National Gallery of Art | Gallery's Building Program | 06/19/73 | $5,000,000 | Washington, DC, United States | Arts and Culture |
