| University of Cape Town | African Cultural Heritage Sites and Landscapes Database | 03/14/08 | $500,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| University of the Witwatersrand | Academic Staff Development | 03/14/08 | $100,000 | Johannesburg, South Africa | International Higher Education and Strategic Projects |
| University of the Western Cape | Mellon Mays Undergraduate Fellowship Program - 10% Increase | 03/19/10 | $22,500 | Bellville, South Africa | Higher Learning |
| University of the Witwatersrand | Mellon Mays Undergraduate Fellowship Program - 10% Increase | 03/19/10 | $22,500 | Johannesburg, South Africa | Higher Learning |
| University of the Western Cape | Doctoral and Postdoctoral Fellowships | 03/10/11 | $300,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | Centre for Rhetoric Studies and Graduate Student Support | 03/15/12 | $320,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| University of the Witwatersrand | Postgraduate Mentoring Program - Phase III | 03/15/12 | $500,000 | Johannesburg, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Humanities Unit | 03/15/12 | $950,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| University of the Western Cape | Research in the Humanities | 03/15/12 | $380,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | Postdoctoral Fellowships - Phase III | 03/14/13 | $275,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Humanities Research - Phase II | 03/13/14 | $700,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | Institute for Humanities in Africa - Phase II | 03/13/14 | $1,286,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| University of the Witwatersrand | Medical Humanities | 03/13/14 | $880,000 | Johannesburg, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | Institute for Creative Arts Renewal | 12/13/18 | $1,000,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Writers/Scholars-in-Residence Programme | 09/06/18 | $679,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| Stellenbosch University | Mellon 30th Anniversary Artists’ Residencies Fellowships | 09/06/18 | $93,000 | Stellenbosch, South Africa | International Higher Education and Strategic Projects |
| University of the Witwatersrand | Supporting a New Generation of African and Diaspora Writers | 09/06/18 | $70,000 | Johannesburg, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | South African Universities Collaboration | 12/09/19 | $773,000 | Cape Town, South Africa | Other |
| University of KwaZulu-Natal | South African Universities Collaboration | 12/09/19 | $681,000 | Westville, South Africa | Other |
| University of the Witwatersrand | Postgraduate Mentoring Program | 03/13/95 | $1,410,000 | Johannesburg, South Africa | Other |
| University of the Witwatersrand | Demography - Migration Node | 06/15/01 | $300,000 | Johannesburg, South Africa | Past Programs |
| Rhodes University | Honors Program | 06/21/02 | $418,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| University of KwaZulu-Natal | Postdoctoral Fellowships | 06/21/02 | $125,000 | Durban, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | Fine Music Radio Series | 07/21/14 | $16,000 | Cape Town, South Africa | Higher Learning |
| University of the Western Cape | Doctoral Support at the World Social Science Forum | 07/27/15 | $45,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
