| Western Cape Tertiary Institutions Trust | Regional Collaborations | 03/15/02 | $100,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| Eastern Seaboard Association of Tertiary Institutions | Research Cluster Program | 03/18/05 | $100,000 | Durban, South Africa | International Higher Education and Strategic Projects |
| University of the Witwatersrand | Academic Staff Development - Phase II | 10/03/13 | $100,000 | Johannesburg, South Africa | International Higher Education and Strategic Projects |
| University of Fort Hare | Merger Office | 06/13/03 | $100,000 | Alice, South Africa | International Higher Education and Strategic Projects |
| University of Fort Hare | Library Collections in the Social Sciences and Humanities | 12/11/07 | $100,000 | Alice, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Women's Academic Solidarity Association | 03/16/07 | $100,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Academic Staff Development | 03/14/08 | $100,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| University of Cape Town | Academic Staff Development | 03/14/08 | $100,000 | Cape Town, South Africa | International Higher Education and Strategic Projects |
| University of KwaZulu-Natal | Academic Staff Development | 03/14/08 | $100,000 | Durban, South Africa | International Higher Education and Strategic Projects |
| University of the Western Cape | Academic Staff Development | 03/14/08 | $100,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Vice-Chancellor Support | 03/16/07 | $100,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Research on Equity and Institutional Culture at Rhodes University | 03/14/13 | $100,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| Stellenbosch University | Academic Staff Development | 03/14/08 | $100,000 | Matieland, South Africa | International Higher Education and Strategic Projects |
| University of the Free State | New Vice-Chancellor Support | 03/10/11 | $100,000 | Bloemfontein, South Africa | International Higher Education and Strategic Projects |
| University of Fort Hare | New Vice-Chancellor Support | 12/17/01 | $100,000 | Alice, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Jazz Heritage Studies & Archive Development | 09/20/10 | $97,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Women's Academic Solidarity Association | 03/10/11 | $95,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| Stellenbosch University | Mellon 30th Anniversary Artists’ Residencies Fellowships | 09/06/18 | $93,000 | Stellenbosch, South Africa | International Higher Education and Strategic Projects |
| WNET | University of Cape Town Opera School Documentary Project | 07/23/12 | $90,000 | New York, NY, United States | International Higher Education and Strategic Projects |
| University of Fort Hare | Library Collection | 01/22/13 | $89,000 | Alice, South Africa | International Higher Education and Strategic Projects |
| Cape Higher Education Consortium | Decolonizing the University | 12/14/15 | $86,000 | Wynberg, South Africa | International Higher Education and Strategic Projects |
| Rhodes University | Cory Library Digitization Project | 10/03/13 | $85,000 | Grahamstown, South Africa | International Higher Education and Strategic Projects |
| Mount Holyoke College | EEP - History of Technology Transfer | 12/17/99 | $80,000 | South Hadley, MA, United States | International Higher Education and Strategic Projects |
| Eastern Seaboard Association of Tertiary Institutions | Regional Cluster Research Program | 03/16/98 | $80,000 | Durban, South Africa | International Higher Education and Strategic Projects |
| Eastern Seaboard Association of Tertiary Institutions | Regional Cluster Research Program | 09/15/00 | $80,000 | Durban, South Africa | International Higher Education and Strategic Projects |
