| University of Virginia | Digital Scholarship | 12/17/99 | $1,000,000 | Charlottesville, VA, United States | Public Knowledge |
| Yale University | Software Preservation Infrastructure | 12/07/17 | $1,000,000 | New Haven, CT, United States | Public Knowledge |
| Ithaka Harbors, Inc. | Core Operations Support - Phase IV | 12/15/06 | $1,000,000 | New York, NY, United States | Public Knowledge |
| University of Illinois at Urbana-Champaign | Strengthening Library Preservation Programs | 12/17/01 | $1,000,000 | Champaign, IL, United States | Public Knowledge |
| Survivors of the Shoah Visual History Foundation | Digital Access | 12/16/02 | $1,000,000 | Los Angeles, CA, United States | Public Knowledge |
| HBCU Library Alliance, Inc. | Building Financial Resilience in the Digital Humanities | 12/10/21 | $1,000,000 | Atlanta, GA, United States | Public Knowledge |
| New York Public Library | Schomburg Endowment | 06/15/01 | $1,000,000 | New York, NY, United States | Public Knowledge |
| The University of Oklahoma | Digital Latin Library - Phase II | 06/04/15 | $1,000,000 | Norman, OK, United States | Public Knowledge |
| Arizona State University | Center for Digital Antiquity and the Digital Archaeological Record | 12/04/14 | $1,000,000 | Tempe, AZ, United States | Public Knowledge |
| University of Illinois at Urbana-Champaign | Developing Text-Mining in the Digital Library - MONK | 12/15/06 | $1,000,000 | Champaign, IL, United States | Public Knowledge |
| Cornell University | Scholarly Resource Semantic Information Store | 12/05/13 | $999,000 | Ithaca, NY, United States | Public Knowledge |
| University of North Carolina Press | Collaborative Services Platform for University Presses | 12/04/14 | $998,000 | Chapel Hill, NC, United States | Public Knowledge |
| Bibliotheque nationale de France | Bibliotheques d'Orient Conservation and Digital Library Program | 12/09/19 | $996,000 | Paris, France | Public Knowledge |
| Council on Library and Information Resources | Postdoctoral Fellowships in Data Curation for Latin American and Caribbean Studies | 06/13/16 | $995,000 | Washington, DC, United States | Public Knowledge |
| Stanford University | Interoperability of Medieval Manuscripts - Phase II | 09/13/12 | $992,000 | Stanford, CA, United States | Public Knowledge |
| New York Public Library | Research Collections and Preservation Consortium (ReCAP) Implementation Phase Two | 12/07/17 | $988,000 | New York, NY, United States | Public Knowledge |
| University of North Carolina at Chapel Hill | Preservation of Southern Audio and Audiovisual Resources - Phase II | 06/04/15 | $986,000 | Chapel Hill, NC, United States | Public Knowledge |
| Universite de Fribourg | Digitizing the Abbey Library of Saint Gall | 12/11/07 | $985,000 | Fribourg, Switzerland | Public Knowledge |
| Council on Library and Information Resources | Postdoctoral Fellowships in Data Curation for Latin American and Caribbean Studies II | 06/01/17 | $981,000 | Washington, DC, United States | Public Knowledge |
| American Historical Association | Gutenberg-e Program | 06/15/01 | $980,000 | Washington, DC, United States | Public Knowledge |
| Michigan State University | Building Financial Resilience in the Digital Humanities | 09/13/21 | $971,000 | East Lansing, MI, United States | Public Knowledge |
| New Mexico Highlands University | Manitos Community Memory: Phase II | 12/11/20 | $970,000 | Las Vegas, NM, United States | Public Knowledge |
| Duke University | Integrating Digital Papyrology - Phase III | 12/09/10 | $958,000 | Durham, NC, United States | Public Knowledge |
| University of California at San Diego | Managing Archival Collections - Phase II | 12/15/06 | $957,000 | La Jolla, CA, United States | Public Knowledge |
| University of North Carolina Press | Open Access History Monograph Initiative | 05/31/18 | $950,000 | Chapel Hill, United States | Public Knowledge |
