| Claremont University Consortium | Center for Digital Humanities | 05/29/12 | $100,000 | Claremont, CA, United States | Higher Learning |
| Dartmouth College | Humanities Faculty Development | 06/16/87 | $500,000 | Hanover, NH, United States | Higher Learning |
| Modern Language Association of America | Humanities Commons | 07/22/13 | $40,500 | New York, NY, United States | Public Knowledge |
| St. Olaf College | Digital Humanities on the Hill | 10/03/13 | $700,000 | Northfield, MN, United States | Higher Learning |
| Carnegie Mellon University | Digital Humanities | 09/11/14 | $2,000,000 | Pittsburgh, PA, United States | Higher Learning |
| Guilford College | Digital Directions for the Arts and Humanities | 09/11/14 | $100,000 | Greensboro, NC, United States | Higher Learning |
| Colby College | Environmental Humanities | 09/15/16 | $800,000 | Waterville, ME, United States | Higher Learning |
| National Humanities Center | Humanities Essays | 10/07/94 | $225,000 | Research Triangle Park, NC, United States | Higher Learning |
| University of the Witwatersrand | Chair of Human Evolution | 12/11/07 | $1,300,000 | Johannesburg, South Africa | International Higher Education and Strategic Projects |
| Syracuse University | Humanities Corridor Bridge | 10/25/10 | $60,000 | Syracuse, NY, United States | Higher Learning |
| University of Washington | Digital Humanities Commons | 12/09/10 | $600,000 | Seattle, WA, United States | Higher Learning |
| American Academy of Arts and Sciences | Humanities Endowment | 12/14/89 | $600,000 | Cambridge, MA, United States | Higher Learning |
| American Council of Learned Societies | Humanities Database | 12/13/93 | $300,000 | New York, NY, United States | Higher Learning |
| Center for Advanced Study in the Behavioral Sciences, Inc. | Humanities Fellowships | 12/18/95 | $1,000,000 | Stanford, CA, United States | Higher Learning |
| Massachusetts Institute of Technology | Digital Humanities | 12/07/17 | $1,300,000 | Cambridge, MA, United States | Higher Learning |
| DePaul University | Experiential Humanities Collaborative | 03/06/19 | $750,000 | Chicago, IL, United States | Higher Learning |
| University of Pennsylvania | Digital Humanities | 03/12/15 | $2,000,000 | Philadelphia, PA, United States | Higher Learning |
| Sterling and Francine Clark Art Institute, Inc. | Humanities Fellowship Endowment | 06/06/13 | $250,000 | Williamstown, MA, United States | Arts and Culture |
| University of Puget Sound | Humanities and Culture in the Digital Age | 06/05/14 | $600,000 | Tacoma, WA, United States | Higher Learning |
| University of New Mexico | Center for Environmental Arts and Humanities | 08/24/22 | $500,000 | Albuquerque, NM, United States | Arts and Culture |
| St. Catherine University | Democratizing the Humanities | 12/08/22 | $497,000 | St. Paul, MN, United States | Higher Learning |
| Catholic University of America | Early Christian Humanism | 06/19/75 | $500,000 | Washington, DC, United States | Higher Learning |
| National Humanities Center | Humanities Conference | 05/11/94 | $30,000 | Research Triangle Park, NC, United States | Higher Learning |
| New College of Florida | Connecting the Arts and Humanities on Florida's Creative Coast | 09/15/16 | $750,000 | Sarasota, FL, United States | Higher Learning |
| Howard University | Humanities Faculty/Curriculum | 10/06/76 | $650,000 | Washington, DC, United States | Higher Learning |
