| Henry Ford College | Transfer Bridges to the Humanities - Phase II | 12/10/21 | $580,000 | Dearborn, MI, United States | Higher Learning |
| American Council on Education | Race and Ethnicity in Higher Education: A Status Report | 12/10/21 | $500,000 | Washington, DC, United States | Higher Learning |
| Craft Emergency Relief Fund, Inc. | Artist Readiness Initiative | 12/10/21 | $500,000 | Montpelier, VT, United States | Arts and Culture |
| New York Botanical Garden | Food Humanities in the Local Community | 12/10/21 | $1,500,000 | Bronx, NY, United States | Higher Learning |
| Cornell University | Prison Education Program - Phase III | 12/10/21 | $1,700,000 | Ithaca, NY, United States | Higher Learning |
| Joyce Theater Foundation, Inc. | Ronald K. Brown/ EVIDENCE, A Dance Company | 12/10/21 | $500,000 | New York, NY, United States | Arts and Culture |
| Dance Iquail, Inc. | Dance for Social Change | 12/10/21 | $475,000 | Philadelphia, PA, United States | Arts and Culture |
| Equal Justice Initiative | Legacy Museum and Gallery | 12/10/21 | $5,000,000 | Montgomery, AL, United States | Other |
| United States Artists, Inc. | Disability Futures | 12/10/21 | $2,500,000 | Chicago, IL, United States | Other |
| HBCU Library Alliance, Inc. | Building Financial Resilience in the Digital Humanities | 12/10/21 | $1,000,000 | Atlanta, GA, United States | Public Knowledge |
| Occidental College | Humanities for Just Communities | 12/10/21 | $1,500,000 | Los Angeles, CA, United States | Higher Learning |
| Morehouse College | Movement, Memory, and Justice Initiative | 12/10/21 | $1,499,000 | Atlanta, GA, United States | Higher Learning |
| San Francisco Public Library | Expanding Information Access for Incarcerated People | 12/10/21 | $2,000,000 | San Francisco , CA, United States | Public Knowledge |
| Libraries Without Borders | ¡Loíza Vive! | 12/10/21 | $200,000 | Washington, DC, United States | Other |
| University of California at Irvine | Community-Centered Archives Practice: Transforming Education, Archives, and Community History | 12/10/21 | $800,000 | Irvine, CA, United States | Public Knowledge |
| University of Luxembourg | Tropy: Digital Image Management Software – Phase III | 12/10/21 | $500,000 | L-4365 Esch-sur-Alzette, Luxembourg | Public Knowledge |
| Mozilla Foundation | Responsible Computer Science Challenge: Humanities/Computing Collaboration Towards Just Tech Futures | 12/10/21 | $2,400,000 | San Francisco, CA, United States | Higher Learning |
| Women in Dialogue | Support for Community-Based Archives | 12/10/21 | $100,000 | Philadelphia, PA, United States | Public Knowledge |
| Museum Hue, Inc. | Museum Hue Capacity Building | 12/10/21 | $200,000 | Brooklyn, NY, United States | Arts and Culture |
| Women’s Housing and Economic Development Corporation | Bronx Music Hall | 12/10/21 | $2,500,000 | Bronx, NY, United States | Humanities in Place |
| Alabama African American Civil Rights Heritage Sites Consortium | Alabama Civil Rights Heritage Sites Consortium | 12/10/21 | $750,000 | Birmingham, AL, United States | Humanities in Place |
| Community Partners | Seminar and Workshop Series on Repatriation and Cultural Heritage Care for Southern California Tribes | 12/10/21 | $550,000 | Los Angeles, CA, United States | Arts and Culture |
| Afro Charities, Inc. | AFRO Archives | 12/10/21 | $1,500,000 | Baltimore, MD, United States | Humanities in Place |
| East-West Players, Inc. | Capacity Building | 12/10/21 | $600,000 | Los Angeles, CA, United States | Arts and Culture |
| Strawberry Mansion Community Development Corporation | John Coltrane House Museum and Cultural Arts Center | 12/10/21 | $500,000 | Philadelphia, PA, United States | Humanities in Place |
